DNM2 monoclonal antibody, clone 5E4C2F3
产品名称: DNM2 monoclonal antibody, clone 5E4C2F3
英文名称: DNM2 monoclonal antibody, clone 5E4C2F3
产品编号: MAB10628
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against partial recombinant DNM2.
- Immunogen:
- Recombinant protein corresponding to human DNM2.
- Host:
- Mouse
- Reactivity:
- Human
- Form:
- Liquid
- Isotype:
- IgG2a
- Storage Buffer:
- In ascites (0.03% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunohistochemistry (1:200-1:1000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
- Western Blot
- Western blot analysis using DNM2 monoclonal antibody, clone 5E4C2F3 (Cat # MAB10628) against truncated DNM2 recombinant protein (1) , SKN-SH cell lysate (2) and NIH/3T3 cell lysate (3) .
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Immunohistochemical analysis of paraffin-embedded human cerebrum tissue (upper) and myelencephalon tissue (bottom) , showing cytoplasmic localization using DNM2 monoclonal antibody, clone 5E4C2F3 (Cat # MAB10628) with DAB staining.
- Entrez GeneID:
- 1785
- Gene Name:
- DNM2
- Gene Alias:
- CMTDI1,CMTDIB,DI-CMTB,DYN2,DYNII
- Gene Description:
- dynamin 2
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Four alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined. [provided by RefSeq
- Other Designations:
- dynamin II
- Gene Pathway